![]() ![]() were unable to determine a cutoff value using the same dataset. Due to the linear correlation between the urinary Na/K ratio and home BP level, Kogure et al. These valuable findings contribute to the practical application of the spot urine Na/K ratio as a marker of hypertension risk.Īnother issue that makes the practical application of the Na/K ratio difficult is the lack of an exact cutoff value. From an analysis of the 1-day to 10-day mean values of the urinary Na/K ratios and home-measured BP levels, they suggested that a measuring period of more than three days would be beneficial. reported the result of an association analysis between multiple daily measured morning urinary Na/K ratios and home BP levels that helped to resolve this unanswered question. According to a study published in this issue of Hypertension Research, Kogure et al. However, it is unclear how many measurements are required to achieve Na/K values that can be relied upon for assessing hypertension risk. According to a previous study, measurements of six random daytime casual urine samples on separate days are necessary to determine the usual Na/K level. ![]() Furthermore, since the Na/K ratio does not require a creatinine value, it can be easily determined with simple equipment that enables the recording of several measurements over the course of a day. Because potassium lowers BP, the Na/K ratio is more closely correlated with concurrently measured BP than sodium alone or dietary sodium intake, as estimated by the Tanaka formula. Recently, great emphasis has been given to the urinary sodium/potassium ratio (Na/K ratio) as another indicator of the burden of sodium on blood pressure (BP). ![]()
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